What is the best way to organise my friends list on Facebook?

[SHAV]

Well, great at least you have knowledge on the list feature.
You can name lists like Family, Friends, Unknown Friends (people you met only once while travelling together in an aircraft), Randoms, etc etc. Also don't forget to create a group for your work management.
So when you want to share stuff on facebook, you will obviously have more privacy, to select which lists can see, and which cannot.
Say if you criticize your work conditions, choose it to be hidden from the Work management list. lol
Hope that helps