Can I 301 re-direct my website homepage to my affiliate link - SEO question?

[Jake]

There are legitimate reasons to redirect to another site that hold up search ranking for a time, I have to think the low ranking power of a typical sales page would sink your home page ranking. Often an intermediate pre-sell page can actually increase conversions, you could just make your home page more of a pitch.

More traditionally one would use Cloaking to show a sales page to everyone but the search spiders, with their increased use of human reviewers and javascript execution it would be a matter of time before that gets exposed, cloaking is a major no-no and would earn a big penalty.