acanthosis nigricans?
|
11-27-2012, 06:39 AM
Post: #2
|
|||
|
|||
It typically occurs in individuals younger than age 40, may be genetically inherited, and is associated with obesity or endocrinopathies, such as hypothyroidism or hyperthyroidism, acromegaly, polycystic ovary disease, insulin-resistant diabetes, or Cushing's disease.
Endocrine The most common cause of acanthosis nigricans is insulin resistance, which leads to increased circulating insulin levels. Insulin spillover into the skin results in its abnormal increase in growth (hyperplasia of the skin) The most common cause of insulin resistance is type 2 diabetes mellitus. Other causes of insulin resistance include obesity, and polycystic ovary syndrome. In the context of a malignant disease, acanthosis nigricans is a paraneoplastic syndrome and is then commonly referred to as acanthosis nigricans maligna. Involvement of mucous membranes is rare and suggests a coexisting malignant condition. When seen in individuals older than age 40, this disorder is commonly associated with an internal malignancy, usually adenocarcinoma, and most commonly of the GI tract or uterus; less commonly of the lung, prostate, breast, or ovary. The stomach is the most common site. Acanthosis nigricans of the oral mucosa or tongue is highly suggestive of a neoplasm, especially of the GI tract. Having said all of the above why should your Facebook be published when there is the internet to research it from the global companies that pay to give us this information.? I am not disputing the fact that you should have it published but it is a hard and expensive road to go down. Good Luck Ads |
|||
« Next Oldest | Next Newest »
|
Messages In This Thread |
acanthosis nigricans? - SharonR - 11-27-2012, 06:31 AM
[] - jackie m - 11-27-2012 06:39 AM
|
User(s) browsing this thread: 1 Guest(s)