I keep getting pop ups?

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I keep getting pop ups on my computer.
i use google chrome but just last week ive seem to get an insane amount of popups on sits i know are safe, like my school website.
how can i get rid of them??

its not an extension thing with chrome because i dont download extensions.
i have no idea what else it could be.
i think i could have downloaded something that could have given me this crap. on internet explore i dont get like the msn homepage i get this website: http://search.conduit.com/?ctid=CT332373...75C1&SSPV=

how do i get rid of this sh*t??